Damamycin Pharmacodynamic yana cikin maganin rigakafi na aminoglycoside, kuma yana da matsakaicin sakamako mai hanawa akan nau'in bacilli iri-iri na gram-korau, kamar escherichia coli, salmonella, shigella, proteus da sauransu. Yana kula da streptococcus, pneumococcus, staphylococcus epidermidis da wasu mycoplasma (kamar mycoplasma gallinarum, mycoplasma turkey, mycoplasma synovialis, da dai sauransu). Yana da mafi yawan rashin jin daɗi ga streptococcus viridis da staphylococcus aureus. Yawancin lokaci yana jure wa pseudomonas aeruginosa da treponemas. Kwayoyin cuta na hanji suna da juriya ga megamycin, amma ba sa nuna juriya da streptomycin. Lincomycin yana da aikin kashe kwayoyin cuta masu kyau akan kwayoyin anaerobic, irin su clostridium, peptococcus, peptostreptococcus, clostridium tetanus, clostridium perfringens da mafi yawan actinomyces. Lincomycin galibi yana aiki ne akan sashin 50s na ribosomes na kwayan cuta, wanda ke shafar haɗin furotin ta hana haɓaka sarkar peptide.
Pharmacokinetics kawai kashi 7% na lincomycin yana sha bayan gudanarwa na ciki, amma yana kiyaye babban taro a cikin sashin gastrointestinal. Tsarin nama da ƙwayoyi ya ƙasa da yawan taro. Ba shi da sauƙi a shigar da ruwan cerebrospinal ko ido, kuma adadin dauri na furotin plasma ba shi da yawa. Yawancin magungunan ana fitar da su ta hanyar tacewa ta glomerular a cikin asalin su. Halin bioavailability na lincomycin shine 30% ~ 40% tare da ƙarancin sha a cikin sarrafa baki. Za a iya rage yawan sha da adadin lincomycin ta hanyar ciyarwa gauraye. An ba kaji 50mg na wannan samfurin (narkar da cikin ruwan sha) kowace kilogiram na nauyin jiki na kwanaki 7. Yayin gwajin, plasma lincomycin ya kai 0.14 μ g/ml, yayin da adadin daguanmycin ya kasance kadan. Bayan kwanaki 7 na gwajin, ya wuce 0.1μg/ml.
1. Haɗe tare da lincomycin, zai iya ƙara yawan aikin ƙwayoyin cuta a kan mycoplasma kuma yana faɗaɗa ƙwayar ƙwayar cuta.
2. Haɗuwa da lincomycin da magungunan anticholinesterase na iya rage tasirin ƙarshen.
3. Haɗe tare da erythromycin yana da tasirin antagonistic.
Magungunan rigakafi. Don kwayoyin cutar Gram-korau, kwayoyin cutar Gram-positive da kamuwa da cutar mycoplasma.
Mixed abin sha: 100g na wannan samfurin gauraye da ruwa 200 ~ 300kg na alade da 50 ~ 100kg na kaza don 3 ~ 5 days. Ciyarwar da aka haɗe: 100g abinci mai gauraya 100kg na alade da 50kg don kaji, ana amfani da shi don kwanaki 5 zuwa 7.
Shuka kula da lafiya: Daga kwanaki 7 kafin bayarwa zuwa kwanaki 7 bayan bayarwa, 100g na wannan samfurin ana haɗe 100kg, ko 200kg da ruwa. Kula da lafiyar Piglet: Kafin da kuma bayan yayewa da reshe, 100g haxa 100kg, ko 200kg ruwa.
Ba a ga wani mummunan halayen ba lokacin amfani da shi bisa ga kayyade amfani da sashi.
