Pharmacodynamics enrofloxacin babban magani ne na ƙwayoyin cuta don dabbobin fluoroquinolone. Yana da tasiri mai kyau akan escherichia coli, salmonella, klebsiella, brucella, pasteurella, actinobacillus pleuropneumoniae, erysipelas, proteus, serratia marcescens, corynebacterium pyogenes, portococcus septicus, staphylococcus aureus, mycoplasma rauni, da dai sauransu. aeruginosa da streptococcus, da kuma rauni mai tasiri akan kwayoyin anaerobic. Yana da tasirin gaske bayan-antibacterial akan ƙwayoyin cuta masu mahimmanci. Tsarin maganin kashe kwayoyin cuta na wannan samfurin shine don hana enzyme rotation na kwayan cuta, tsoma baki tare da kwafin DNA na kwayan cuta, rubutawa da gyara sake haɗewa, ƙwayoyin cuta ba za su iya girma da haifuwa kullum kuma su mutu ba.
Pharmacokinetics sha na intramuscular na wannan samfurin yana da sauri kuma cikakke, tare da bioavailability na 91.9% a cikin aladu da 82% a cikin shanun kiwo. An rarraba shi sosai a cikin dabbobi kuma yana iya shigar da kyallen takarda da ruwan jiki da kyau, sai dai ruwan cerebrospinal, ƙaddamar da ƙwayoyi a kusan dukkanin kyallen takarda ya fi na plasma. Metabolism na hanta shine yafi samar da ciprofloxacin ta hanyar cire ethyl na zobe na 7-piperazine, sannan oxidation da glucuronic acid daurin. Mafi yawa ana fitar da shi ta hanyar koda (ta hanyar ɓoye tubule na renal da tacewa na glomerular), kuma 15% zuwa 50% ana fitar da shi daga fitsari a sigar asali. Kawar da rabin rayuwar ya bambanta sosai a cikin nau'o'in nau'i daban-daban da kuma hanyoyin gudanarwa daban-daban. Kawar da rabin rayuwa bayan allurar intramuscular shine awanni 5.9 a cikin shanu, awanni 9.9 a cikin dawakai, awanni 1.5 zuwa 4.5 a cikin tumaki, da awanni 4.6 a alade.
1. Wannan samfurin yana da tasirin daidaitawa lokacin amfani da aminoglycoside ko penicillin mai faɗi.
2. ions karfe masu nauyi irin su ca2+, mg2+, fe3+ da al3+ canchelate tare da wannan samfurin kuma suna shafar sha.
3. Lokacin da aka haɗe shi da theophylline da maganin kafeyin, zai iya rage adadin dauri na furotin plasma, haɓaka haɓakar theophylline da maganin kafeyin a cikin jini sosai, har ma ya bayyana alamun guba na theophylline.
4. Wannan samfurin yana da sakamako na hana hanta miyagun ƙwayoyi enzymes, wanda zai iya rage yarda kudi na kwayoyi, yafi metabolized a cikin hanta da kuma ƙara jini miyagun ƙwayoyi maida hankali.
Fluoroquinolone antibacterial kwayoyi. Ana amfani dashi don cututtukan cututtukan cututtukan cututtukan dabbobi da kaji da cututtukan mycoplasma.
Intramuscularly allura: kashi daya, 0.025ml da 1kg nauyin jiki na shanu, tumaki da alade; 0.025 ~ 0.05ml don karnuka, kuliyoyi da zomaye. Yi amfani da sau 1 zuwa 2 a rana don kwanaki 2 zuwa 3.
1. Ragewar guringuntsi a cikin kananan dabbobi, yana shafar ci gaban kashi da haifar da gurguwa da zafi.
2. Halin tsarin narkewar abinci ya hada da amai, rashin cin abinci, gudawa da sauri.
3. Halayen fata sun haɗa da erythema, pruritus, urticaria da kuma hotuna.
4. Allergic halayen, ataxia, seizures ana gani a cikin karnuka da kuliyoyi.
1. Yana da tasiri mai tasiri mai tasiri akan tsarin tsakiya, yana haifar da cututtuka na epileptic, kuma ya kamata a yi amfani da shi tare da taka tsantsan a cikin karnuka masu farfaɗiya.
2. Ya kamata a yi amfani da masu naman dabbobi da dabbobi marasa aikin koda tare da taka tsantsan, wanda zai iya haifar da fitsari lokaci-lokaci.
3. Wannan samfurin bai dace da dawakai ba. Intramuscular injections ne na wucin gadi irritants.
4. Kada a yi amfani da wannan samfurin a cikin karnuka kafin makonni 8.
5. Maganin juriya na miyagun ƙwayoyi na wannan samfurin yana karuwa kuma bai kamata a yi amfani da shi a cikin allurai na subtherapeutic na dogon lokaci.
